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Dysfunctional epileptic neuronal circuits and dysmorphic dendritic spines are mitigated by platelet-activating factor receptor antagonism
Temporal lobe epilepsy or limbic epilepsy lacks effective therapies due to a void in understanding the cellular and molecular mechanisms that set in motion aberrant neuronal network formations during the course of limbic epileptogenesis (LE). Here we show in in vivo rodent models of LE that the phos...
Autores principales: | Musto, Alberto E., Rosencrans, Robert F., Walker, Chelsey P., Bhattacharjee, Surjyadipta, Raulji, Chittalsinh M., Belayev, Ludmila, Fang, Zhide, Gordon, William C., Bazan, Nicolas G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957208/ https://www.ncbi.nlm.nih.gov/pubmed/27444269 http://dx.doi.org/10.1038/srep30298 |
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