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Fibroblast growth factor rescues brain endothelial cells lacking presenilin 1 from apoptotic cell death following serum starvation

Presenilin 1 (Psen1) is important for vascular brain development and is known to influence cellular stress responses. To understand the role of Psen1 in endothelial stress responses, we investigated the effects of serum withdrawal on wild type (wt) and Psen1−/− embryonic brain endothelial cells. Ser...

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Detalles Bibliográficos
Autores principales: Gama Sosa, Miguel A., De Gasperi, Rita, Hof, Patrick R., Elder, Gregory A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957214/
https://www.ncbi.nlm.nih.gov/pubmed/27443835
http://dx.doi.org/10.1038/srep30267