The first non Clostridial botulinum-like toxin cleaves VAMP within the juxtamembrane domain

The genome of Weissella oryzae SG25T was recently sequenced and a botulinum neurotoxin (BoNT) like gene was identified by bioinformatics methods. The typical three-domains organization of BoNTs with a N-terminal metalloprotease domain, a translocation and a cell binding domains could be identified....

Descripción completa

Detalles Bibliográficos
Autores principales: Zornetta, Irene, Azarnia Tehran, Domenico, Arrigoni, Giorgio, Anniballi, Fabrizio, Bano, Luca, Leka, Oneda, Zanotti, Giuseppe, Binz, Thomas, Montecucco, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957215/
https://www.ncbi.nlm.nih.gov/pubmed/27443638
http://dx.doi.org/10.1038/srep30257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957215/
https://www.ncbi.nlm.nih.gov/pubmed/27443638
http://dx.doi.org/10.1038/srep30257

Ejemplares similares