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Mechanistic Studies on the Stereoselectivity of the Serotonin 5‐HT(1A) Receptor

G‐protein‐coupled receptors (GPCRs) are involved in a wide range of physiological processes, and they have attracted considerable attention as important targets for developing new medicines. A central and largely unresolved question in drug discovery, which is especially relevant to GPCRs, concerns...

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Detalles Bibliográficos
Autores principales: Yuan, Shuguang, Peng, Qian, Palczewski, Krzysztof, Vogel, Horst, Filipek, Slawomir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957245/
https://www.ncbi.nlm.nih.gov/pubmed/27244650
http://dx.doi.org/10.1002/anie.201603766