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Mutation load under additive fitness effects
Under the traditional mutation load model based on multiplicative fitness effects, the load in a population is 1−e(−U), where U is the genomic deleterious mutation rate. Because this load becomes high under large U, synergistic epistasis has been proposed as one possible means of reducing the load....
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cambridge University Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957254/ https://www.ncbi.nlm.nih.gov/pubmed/26788801 http://dx.doi.org/10.1017/S0016672314000226 |