Advantages of Bayesian monitoring methods in deciding whether and when to stop a clinical trial: an example of a neonatal cooling trial

BACKGROUND: Decisions to stop randomized trials are often based on traditional P value thresholds and are often unconvincing to clinicians. To familiarize clinical investigators with the application and advantages of Bayesian monitoring methods, we illustrate the steps of Bayesian interim analysis u...

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Detalles Bibliográficos
Autores principales: Pedroza, Claudia, Tyson, Jon E., Das, Abhik, Laptook, Abbot, Bell, Edward F., Shankaran, Seetha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957277/
https://www.ncbi.nlm.nih.gov/pubmed/27450203
http://dx.doi.org/10.1186/s13063-016-1480-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957277/
https://www.ncbi.nlm.nih.gov/pubmed/27450203
http://dx.doi.org/10.1186/s13063-016-1480-4

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