Boosting the discriminatory power of sparse survival models via optimization of the concordance index and stability selection

BACKGROUND: When constructing new biomarker or gene signature scores for time-to-event outcomes, the underlying aims are to develop a discrimination model that helps to predict whether patients have a poor or good prognosis and to identify the most influential variables for this task. In practice, t...

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Detalles Bibliográficos
Autores principales: Mayr, Andreas, Hofner, Benjamin, Schmid, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957316/
https://www.ncbi.nlm.nih.gov/pubmed/27444890
http://dx.doi.org/10.1186/s12859-016-1149-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957316/
https://www.ncbi.nlm.nih.gov/pubmed/27444890
http://dx.doi.org/10.1186/s12859-016-1149-8

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