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Genetic alteration and mutation profiling of circulating cell-free tumor DNA (cfDNA) for diagnosis and targeted therapy of gastrointestinal stromal tumors

Gastrointestinal stromal tumors (GISTs) have been recognized as a biologically distinctive type of tumor, different from smooth muscle and neural tumors of the gastrointestinal tract. The identification of genetic aberrations in proto-oncogenes that drive the growth of GISTs is critical for improvin...

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Detalles Bibliográficos
Autores principales: Yan, Weixin, Zhang, Aiguo, Powell, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957326/
https://www.ncbi.nlm.nih.gov/pubmed/27443349
http://dx.doi.org/10.1186/s40880-016-0131-1