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A proof-of-concept clinical study examining the NRF2 activator sulforaphane against neutrophilic airway inflammation

Sulforaphane (SFN), a naturally occurring isothiocyanate found in cruciferous vegetables, is implicated as a possible therapy for airway inflammation via induction of the transcription factor NF-E2-related factor 2 (NRF2). In this proof-of-concept clinical study, we show that supplementation of SFN...

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Detalles Bibliográficos
Autores principales: Duran, Charity G., Burbank, Allison J., Mills, Katherine H., Duckworth, Heather R., Aleman, Maria M., Kesic, Matthew J., Peden, David B., Pan, Yinghao, Zhou, Haibo, Hernandez, Michelle L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957339/
https://www.ncbi.nlm.nih.gov/pubmed/27450419
http://dx.doi.org/10.1186/s12931-016-0406-8