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The Domestic Ferret (Mustela putorius furo) as a Lethal Infection Model for 3 Species of Ebolavirus

Small-animal models have been developed for several Filoviridae species; however, serial adaptation was required to produce lethal infection. These adapted viruses have sequence changes in several genes, including those that modulate the host immune response. Nonhuman primate models do not require a...

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Detalles Bibliográficos
Autores principales: Cross, Robert W., Mire, Chad E., Borisevich, Viktoriya, Geisbert, Joan B., Fenton, Karla A., Geisbert, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957446/
https://www.ncbi.nlm.nih.gov/pubmed/27354371
http://dx.doi.org/10.1093/infdis/jiw209