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Serological Evidence of Immune Priming by Group A Streptococci in Patients with Acute Rheumatic Fever

Acute rheumatic fever (ARF) is an autoimmune response to Group A Streptococcus (GAS) infection. Repeated GAS exposures are proposed to ‘prime’ the immune system for autoimmunity. This notion of immune-priming by multiple GAS infections was first postulated in the 1960s, but direct experimental evide...

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Detalles Bibliográficos
Autores principales: Raynes, Jeremy M., Frost, Hannah R. C., Williamson, Deborah A., Young, Paul G., Baker, Edward N., Steemson, John D., Loh, Jacelyn M., Proft, Thomas, Dunbar, P. R., Atatoa Carr, Polly E., Bell, Anita, Moreland, Nicole J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957554/
https://www.ncbi.nlm.nih.gov/pubmed/27499748
http://dx.doi.org/10.3389/fmicb.2016.01119