Quantitative assessment of chromosome instability induced through chemical disruption of mitotic progression

Most solid tumors are aneuploid, carrying an abnormal number of chromosomes, and they frequently missegregate whole chromosomes in a phenomenon termed chromosome instability (CIN). While CIN can be provoked through disruption of numerous mitotic pathways, it is not clear which of these mechanisms ar...

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Detalles Bibliográficos
Autores principales: Markossian, Sarine, Arnaoutov, Alexei, Saba, Nakhle S., Larionov, Vladimir, Dasso, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957569/
https://www.ncbi.nlm.nih.gov/pubmed/27104376
http://dx.doi.org/10.1080/15384101.2016.1175796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957569/
https://www.ncbi.nlm.nih.gov/pubmed/27104376
http://dx.doi.org/10.1080/15384101.2016.1175796

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