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Tunable recombinant protein expression in E. coli: enabler for continuous processing?

Tuning of transcription is a powerful process technological tool for efficient recombinant protein production in Escherichia coli. Many challenges such as product toxicity, formation of inclusion bodies, cell death, and metabolic burden are associated with non-suitable (too high or too low) levels o...

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Detalles Bibliográficos
Autores principales: Marschall, Lukas, Sagmeister, Patrick, Herwig, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957632/
https://www.ncbi.nlm.nih.gov/pubmed/27170324
http://dx.doi.org/10.1007/s00253-016-7550-4