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Tunable recombinant protein expression in E. coli: enabler for continuous processing?
Tuning of transcription is a powerful process technological tool for efficient recombinant protein production in Escherichia coli. Many challenges such as product toxicity, formation of inclusion bodies, cell death, and metabolic burden are associated with non-suitable (too high or too low) levels o...
Autores principales: | Marschall, Lukas, Sagmeister, Patrick, Herwig, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957632/ https://www.ncbi.nlm.nih.gov/pubmed/27170324 http://dx.doi.org/10.1007/s00253-016-7550-4 |
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