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Catalytic enantioselective addition of organoboron reagents to fluoroketones controlled by electrostatic interactions

Organofluorine compounds are central to modern chemistry, and broadly applicable transformations that generate them efficiently and enantioselectively are in much demand. Here we introduce efficient catalytic methods for additions of allyl and allenyl organoboron reagents to fluorine-substituted ket...

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Detalles Bibliográficos
Autores principales: Lee, KyungA, Silverio, Daniel L., Torker, Sebastian, Robbins, Daniel W., Haeffner, Fredrik, van der Mei, Farid W., Hoveyda, Amir H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957664/
https://www.ncbi.nlm.nih.gov/pubmed/27442282
http://dx.doi.org/10.1038/nchem.2523