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Neutrophils from patients with SAPHO syndrome show no signs of aberrant NADPH oxidase-dependent production of intracellular reactive oxygen species

Objective. We aimed to investigate if aberrant intracellular production of NADPH oxidase-derived reactive oxygen species (ROS) in neutrophils is a disease mechanism in the autoinflammatory disease SAPHO syndrome, characterized by synovitis, acne, pustulosis, hyperostosis and osteitis, as has previou...

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Detalles Bibliográficos
Autores principales: Wekell, Per, Björnsdottir, Halla, Björkman, Lena, Sundqvist, Martina, Christenson, Karin, Osla, Veronica, Berg, Stefan, Fasth, Anders, Welin, Amanda, Bylund, Johan, Karlsson, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957673/
https://www.ncbi.nlm.nih.gov/pubmed/27121779
http://dx.doi.org/10.1093/rheumatology/kew192