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Thrombotic microangiopathy and human immunodeficiency virus in the era of eculizumab

Thrombotic microangiopathies (TMAs) include thrombotic thromobocytopenic purpura and hemolytic uremic syndrome (HUS). Among these conditions, atypical HUS is now recognized to be a disease of alternative complement pathway dysregulation. Eculizumab is a recombinant humanized monoclonal antibody that...

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Detalles Bibliográficos
Autores principales: Jin, Anna, Boroujerdi-Rad, Laleh, Shah, Gaurang, Chen, Joline L.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957717/
https://www.ncbi.nlm.nih.gov/pubmed/27478600
http://dx.doi.org/10.1093/ckj/sfw035