The Replication of Frataxin Gene Is Assured by Activation of Dormant Origins in the Presence of a GAA-Repeat Expansion

It is well known that DNA replication affects the stability of several trinucleotide repeats, but whether replication profiles of human loci carrying an expanded repeat differ from those of normal alleles is poorly understood in the endogenous context. We investigated this issue using cell lines fro...

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Detalles Bibliográficos
Autores principales: Stevanoni, Martina, Palumbo, Elisa, Russo, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957762/
https://www.ncbi.nlm.nih.gov/pubmed/27447727
http://dx.doi.org/10.1371/journal.pgen.1006201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957762/
https://www.ncbi.nlm.nih.gov/pubmed/27447727
http://dx.doi.org/10.1371/journal.pgen.1006201

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