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The Roles of RNA Polymerase I and III Subunits Polr1c and Polr1d in Craniofacial Development and in Zebrafish Models of Treacher Collins Syndrome

Ribosome biogenesis is a global process required for growth and proliferation of all cells, yet perturbation of ribosome biogenesis during human development often leads to tissue-specific defects termed ribosomopathies. Transcription of the ribosomal RNAs (rRNAs) by RNA polymerases (Pol) I and III,...

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Detalles Bibliográficos
Autores principales: Noack Watt, Kristin E., Achilleos, Annita, Neben, Cynthia L., Merrill, Amy E., Trainor, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957770/
https://www.ncbi.nlm.nih.gov/pubmed/27448281
http://dx.doi.org/10.1371/journal.pgen.1006187