Retinal Neuroprotective Effects of Flibanserin, an FDA-Approved Dual Serotonin Receptor Agonist-Antagonist

PURPOSE: To assess the neuroprotective effects of flibanserin (formerly BIMT-17), a dual 5-HT(1A) agonist and 5-HT(2A) antagonist, in a light-induced retinopathy model. METHODS: Albino BALB/c mice were injected intraperitoneally with either vehicle or increasing doses of flibanserin ranging from 0.7...

Descripción completa

Detalles Bibliográficos
Autores principales: Coyner, Aaron S., Ryals, Renee C., Ku, Cristy A., Fischer, Cody M., Patel, Rachel C., Datta, Shreya, Yang, Paul, Wen, Yuquan, Hen, René, Pennesi, Mark E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957778/
https://www.ncbi.nlm.nih.gov/pubmed/27447833
http://dx.doi.org/10.1371/journal.pone.0159776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957778/
https://www.ncbi.nlm.nih.gov/pubmed/27447833
http://dx.doi.org/10.1371/journal.pone.0159776

Ejemplares similares