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Borneol Is a TRPM8 Agonist that Increases Ocular Surface Wetness

Borneol is a compound widely used in ophthalmic preparations in China. Little is known about its exact role in treating eye diseases. Here we report that transient receptor potential melastatin 8 (TRPM8) channel is a pharmacological target of borneol and mediates its therapeutic effect in the eyes....

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Detalles Bibliográficos
Autores principales: Chen, Gui-Lan, Lei, Ming, Zhou, Lu-Ping, Zeng, Bo, Zou, Fangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957794/
https://www.ncbi.nlm.nih.gov/pubmed/27448228
http://dx.doi.org/10.1371/journal.pone.0158868