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Control of the Inflammatory Macrophage Transcriptional Signature by miR-155

Inflammatory M1 spectrum macrophages protect from infection but can cause inflammatory disease and tissue damage, whereas alternatively activated/M2 spectrum macrophages reduce inflammation and promote tissue repair. Modulation of macrophage phenotype may be therapeutically beneficial and requires f...

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Detalles Bibliográficos
Autores principales: Jablonski, Kyle A., Gaudet, Andrew D., Amici, Stephanie A., Popovich, Phillip G., Guerau-de-Arellano, Mireia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957803/
https://www.ncbi.nlm.nih.gov/pubmed/27447824
http://dx.doi.org/10.1371/journal.pone.0159724