Modulation of therapy-induced senescence by reactive lipid aldehydes

Current understanding points to unrepairable chromosomal damage as the critical determinant of accelerated senescence in cancer cells treated with radiation or chemotherapy. Nonetheless, the potent senescence inducer etoposide not only targets topoisomerase II to induce DNA damage but also produces...

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Detalles Bibliográficos
Autores principales: Flor, A C, Doshi, A P, Kron, S J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957821/
https://www.ncbi.nlm.nih.gov/pubmed/27453792
http://dx.doi.org/10.1038/cddiscovery.2016.45

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957821/
https://www.ncbi.nlm.nih.gov/pubmed/27453792
http://dx.doi.org/10.1038/cddiscovery.2016.45

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