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In vitro selection of Plasmodium falciparum Pfcrt and Pfmdr1 variants by artemisinin

BACKGROUND: Anti-malarial drugs are the major focus in the prevention and treatment of malaria. Artemisinin-based combination therapy (ACT) is the WHO recommended first-line treatment for Plasmodium falciparum malaria across the endemic world. Also ACT is increasingly relied upon in treating Plasmod...

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Detalles Bibliográficos
Autores principales: Njokah, Muturi J., Kang’ethe, Joseph N., Kinyua, Johnson, Kariuki, Daniel, Kimani, Francis T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957835/
https://www.ncbi.nlm.nih.gov/pubmed/27449110
http://dx.doi.org/10.1186/s12936-016-1443-y