Isavuconazole Population Pharmacokinetic Analysis Using Nonparametric Estimation in Patients with Invasive Fungal Disease (Results from the VITAL Study)

Isavuconazonium sulfate (Cresemba; Astellas Pharma Inc.), a water-soluble prodrug of the triazole antifungal agent isavuconazole, is available for the treatment of invasive aspergillosis (IA) and invasive mucormycosis. A population pharmacokinetic (PPK) model was constructed using nonparametric esti...

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Detalles Bibliográficos
Autores principales: Kovanda, Laura L., Desai, Amit V., Lu, Qiaoyang, Townsend, Robert W., Akhtar, Shahzad, Bonate, Peter, Hope, William W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958143/
https://www.ncbi.nlm.nih.gov/pubmed/27185799
http://dx.doi.org/10.1128/AAC.00514-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958143/
https://www.ncbi.nlm.nih.gov/pubmed/27185799
http://dx.doi.org/10.1128/AAC.00514-16

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