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The N-terminus of survivin is a mitochondrial-targeting sequence and Src regulator

Survivin (also known as BIRC5) is a cancer-associated protein that exists in several locations in the cell. Its cytoplasmic residence in interphase cells is governed by CRM1 (also known as XPO1)-mediated nuclear exportation, and its localisation during mitosis to the centromeres and midzone microtub...

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Detalles Bibliográficos
Autores principales: Dunajová, Lucia, Cash, Emily, Markus, Robert, Rochette, Sophie, Townley, Amelia R., Wheatley, Sally P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958295/
https://www.ncbi.nlm.nih.gov/pubmed/27246243
http://dx.doi.org/10.1242/jcs.183277