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Long-term drug administration in the adult zebrafish using oral gavage for cancer preclinical studies

Zebrafish are a major model for chemical genetics, and most studies use embryos when investigating small molecules that cause interesting phenotypes or that can rescue disease models. Limited studies have dosed adults with small molecules by means of water-borne exposure or injection techniques. Cha...

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Detalles Bibliográficos
Autores principales: Dang, Michelle, Henderson, Rachel E., Garraway, Levi A., Zon, Leonard I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958307/
https://www.ncbi.nlm.nih.gov/pubmed/27482819
http://dx.doi.org/10.1242/dmm.024166