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Hallmarks of progeroid syndromes: lessons from mice and reprogrammed cells
Ageing is a process that inevitably affects most living organisms and involves the accumulation of macromolecular damage, genomic instability and loss of heterochromatin. Together, these alterations lead to a decline in stem cell function and to a reduced capability to regenerate tissue. In recent y...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958309/ https://www.ncbi.nlm.nih.gov/pubmed/27482812 http://dx.doi.org/10.1242/dmm.024711 |