Cargando…

Hallmarks of progeroid syndromes: lessons from mice and reprogrammed cells

Ageing is a process that inevitably affects most living organisms and involves the accumulation of macromolecular damage, genomic instability and loss of heterochromatin. Together, these alterations lead to a decline in stem cell function and to a reduced capability to regenerate tissue. In recent y...

Descripción completa

Detalles Bibliográficos
Autores principales: Carrero, Dido, Soria-Valles, Clara, López-Otín, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958309/
https://www.ncbi.nlm.nih.gov/pubmed/27482812
http://dx.doi.org/10.1242/dmm.024711