Pins is not required for spindle orientation in the Drosophila wing disc

In animal cells, mitotic spindles are oriented by the dynein/dynactin motor complex, which exerts a pulling force on astral microtubules. Dynein/dynactin localization depends on Mud/NUMA, which is typically recruited to the cortex by Pins/LGN. In Drosophila neuroblasts, the Inscuteable/Baz/Par-6/aPK...

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Detalles Bibliográficos
Autores principales: Bergstralh, Dan T., Lovegrove, Holly E., Kujawiak, Izabela, Dawney, Nicole S., Zhu, Jinwei, Cooper, Samantha, Zhang, Rongguang, St Johnston, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958339/
https://www.ncbi.nlm.nih.gov/pubmed/27287805
http://dx.doi.org/10.1242/dev.135475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958339/
https://www.ncbi.nlm.nih.gov/pubmed/27287805
http://dx.doi.org/10.1242/dev.135475

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