Rational design and synthesis of novel diphenyl ether derivatives as antitubercular agents

A series of triclosan mimic diphenyl ether derivatives have been synthesized and evaluated for their in vitro antitubercular activity against Mycobacterium tuberculosis H37Rv. The binding mode of the compounds at the active site of enoyl-acyl carrier protein reductase of M. tuberculosis has been exp...

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Detalles Bibliográficos
Autores principales: Kar, Sidhartha S, Bhat G, Varadaraj, Rao, Praveen PN, Shenoy, Vishnu P, Bairy, Indira, Shenoy, G Gautham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958353/
https://www.ncbi.nlm.nih.gov/pubmed/27486307
http://dx.doi.org/10.2147/DDDT.S104037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958353/
https://www.ncbi.nlm.nih.gov/pubmed/27486307
http://dx.doi.org/10.2147/DDDT.S104037

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