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The unfolded protein response: mechanisms and therapy of neurodegeneration
Activation of the unfolded protein response is emerging as a common theme in protein-misfolding neurodegenerative diseases, with relevant markers observed in patient tissue and mouse models. Genetic and pharmacological manipulation of the pathway in several mouse models has shown that this is not a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958893/ https://www.ncbi.nlm.nih.gov/pubmed/27190028 http://dx.doi.org/10.1093/brain/aww101 |