Combretastatin A-4 efficiently inhibits angiogenesis and induces neuronal apoptosis in zebrafish

Cis-stilbene combretastatin A-4 (CA-4) and a large group of its derivant compounds have been shown significant anti-angiogenesis activity. However the side effects even the toxicities of these chemicals were not evaluated adequately. The zebrafish model has become an important vertebrate model for e...

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Detalles Bibliográficos
Autores principales: Shi, Yun-Wei, Yuan, Wei, Wang, Xin, Gong, Jie, Zhu, Shun-Xing, Chai, Lin-Lin, Qi, Jia-Ling, Qin, Yin-Yin, Gao, Yu, Zhou, Yu-Ling, Fan, Xiao-Le, Ji, Chun-Ya, Wu, Jia-Yi, Wang, Zhi-Wei, Liu, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958954/
https://www.ncbi.nlm.nih.gov/pubmed/27452835
http://dx.doi.org/10.1038/srep30189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958954/
https://www.ncbi.nlm.nih.gov/pubmed/27452835
http://dx.doi.org/10.1038/srep30189

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