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Combretastatin A-4 efficiently inhibits angiogenesis and induces neuronal apoptosis in zebrafish
Cis-stilbene combretastatin A-4 (CA-4) and a large group of its derivant compounds have been shown significant anti-angiogenesis activity. However the side effects even the toxicities of these chemicals were not evaluated adequately. The zebrafish model has become an important vertebrate model for e...
Autores principales: | Shi, Yun-Wei, Yuan, Wei, Wang, Xin, Gong, Jie, Zhu, Shun-Xing, Chai, Lin-Lin, Qi, Jia-Ling, Qin, Yin-Yin, Gao, Yu, Zhou, Yu-Ling, Fan, Xiao-Le, Ji, Chun-Ya, Wu, Jia-Yi, Wang, Zhi-Wei, Liu, Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958954/ https://www.ncbi.nlm.nih.gov/pubmed/27452835 http://dx.doi.org/10.1038/srep30189 |
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