PACSIN2 polymorphism is associated with thiopurine-induced hematological toxicity in children with acute lymphoblastic leukaemia undergoing maintenance therapy

Adequate maintenance therapy for childhood acute lymphoblastic leukemia (ALL), with 6-mercaptopurine as an essential component, is necessary for retaining durable remission. Interruptions or discontinuations of the therapy due to drug-related toxicities, which can be life threatening, may result in...

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Detalles Bibliográficos
Autores principales: Smid, Alenka, Karas-Kuzelicki, Natasa, Jazbec, Janez, Mlinaric-Rascan, Irena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958958/
https://www.ncbi.nlm.nih.gov/pubmed/27452984
http://dx.doi.org/10.1038/srep30244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958958/
https://www.ncbi.nlm.nih.gov/pubmed/27452984
http://dx.doi.org/10.1038/srep30244

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