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The inhibition of calpains ameliorates vascular restenosis through MMP2/TGF-β1 pathway

Restenosis limits the efficacy of vascular percutaneous intervention, in which vascular smooth muscle cell (VSMC) proliferation and activation of inflammation are two primary causal factors. Calpains influence VSMC proliferation and collagen synthesis. However, the roles of calpastatin and calpains...

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Detalles Bibliográficos
Autores principales: Tang, Lianghu, Pei, Haifeng, Yang, Yi, Wang, Xiong, Wang, Ting, Gao, Erhe, Li, De, Yang, Yongjian, Yang, Dachun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958998/
https://www.ncbi.nlm.nih.gov/pubmed/27453531
http://dx.doi.org/10.1038/srep29975