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Peripheral Administration of a Long-Acting Peptide Oxytocin Receptor Agonist Inhibits Fear-Induced Freezing

Oxytocin (OT) modulates the expression of social and emotional behaviors and consequently has been proposed as a pharmacologic treatment of psychiatric diseases, including autism spectrum disorders and schizophrenia; however, endogenous OT has a short half-life in plasma and poor permeability across...

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Detalles Bibliográficos
Autores principales: Modi, Meera E., Majchrzak, Mark J., Fonseca, Kari R., Doran, Angela, Osgood, Sarah, Vanase-Frawley, Michelle, Feyfant, Eric, McInnes, Heather, Darvari, Ramin, Buhl, Derek L., Kablaoui, Natasha M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959095/
https://www.ncbi.nlm.nih.gov/pubmed/27217590
http://dx.doi.org/10.1124/jpet.116.232702