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Cations Stiffen Actin Filaments by Adhering a Key Structural Element to Adjacent Subunits

[Image: see text] Ions regulate the assembly and mechanical properties of actin filaments. Recent work using structural bioinformatics and site-specific mutagenesis favors the existence of two discrete and specific divalent cation binding sites on actin filaments, positioned in the long axis between...

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Detalles Bibliográficos
Autores principales: Hocky, Glen M., Baker, Joseph L., Bradley, Michael J., Sinitskiy, Anton V., De La Cruz, Enrique M., Voth, Gregory A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959277/
https://www.ncbi.nlm.nih.gov/pubmed/27146246
http://dx.doi.org/10.1021/acs.jpcb.6b02741