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Approximate parameter inference in systems biology using gradient matching: a comparative evaluation
BACKGROUND: A challenging problem in current systems biology is that of parameter inference in biological pathways expressed as coupled ordinary differential equations (ODEs). Conventional methods that repeatedly numerically solve the ODEs have large associated computational costs. Aimed at reducing...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959362/ https://www.ncbi.nlm.nih.gov/pubmed/27454253 http://dx.doi.org/10.1186/s12938-016-0186-x |