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HBX Protein-Induced Downregulation of microRNA-18a is Responsible for Upregulation of Connective Tissue Growth Factor in HBV Infection-Associated Hepatocarcinoma

BACKGROUND: This study was designed to improve our understanding of the role of miR-18a and its target (connective tissue growth factor (CTGF), which are mediators in HBX-induced hepatocellular carcinoma (HCC). MATERIAL/METHODS: We first investigated the expression of several candidate microRNAs (mi...

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Detalles Bibliográficos
Autores principales: Liu, Xiaomin, Zhang, Yingjian, Wang, Ping, Wang, Hongyun, Su, Huanhuan, Zhou, Xin, Zhang, Lamei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959457/
https://www.ncbi.nlm.nih.gov/pubmed/27421245
http://dx.doi.org/10.12659/MSM.895943