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Apolipoprotein L1 Variant Associated with Increased Susceptibility to Trypanosome Infection

African trypanosomes, except Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense, which cause human African trypanosomiasis, are lysed by the human serum protein apolipoprotein L1 (ApoL1). These two subspecies can resist human ApoL1 because they express the serum resistance proteins T. b...

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Detalles Bibliográficos
Autores principales: Cuypers, Bart, Lecordier, Laurence, Meehan, Conor J., Van den Broeck, Frederik, Imamura, Hideo, Büscher, Philippe, Dujardin, Jean-Claude, Laukens, Kris, Schnaufer, Achim, Dewar, Caroline, Lewis, Michael, Balmer, Oliver, Azurago, Thomas, Kyei-Faried, Sardick, Ohene, Sally-Ann, Duah, Boateng, Homiah, Prince, Mensah, Ebenezer Kofi, Anleah, Francis, Franco, Jose Ramon, Pays, Etienne, Deborggraeve, Stijn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959518/
https://www.ncbi.nlm.nih.gov/pubmed/27073096
http://dx.doi.org/10.1128/mBio.02198-15