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JAK2 inhibitor combined with DC-activated AFP-specific T-cells enhances antitumor function in a Fas/FasL signal-independent pathway

OBJECTIVE: Combination therapy for cancer is more effective than using only standard chemo- or radiotherapy. Our previous results showed that dendritic cell-activated α-fetoprotein (AFP)-specific T-cells inhibit tumor in vitro and in vivo. In this study, we focused on antitumor function of CD8(+) T-...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Wang, Yue-ru, Ding, Guang-hui, Yang, Ting-song, Yao, Le, Hua, Jie, He, Zhi-gang, Qian, Ming-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959582/
https://www.ncbi.nlm.nih.gov/pubmed/27499636
http://dx.doi.org/10.2147/OTT.S97941