Lapatinib induces autophagic cell death and differentiation in acute myeloblastic leukemia

Lapatinib is an oral-form dual tyrosine kinase inhibitor of epidermal growth factor receptor (EGFR or ErbB/Her) superfamily members with anticancer activity. In this study, we examined the effects and mechanism of action of lapatinib on several human leukemia cells lines, including acute myeloid leu...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Jen, Fang, Li-Wen, Su, Wen-Chi, Hsu, Wen-Yi, Yang, Kai-Chien, Huang, Huey-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959590/
https://www.ncbi.nlm.nih.gov/pubmed/27499639
http://dx.doi.org/10.2147/OTT.S105664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959590/
https://www.ncbi.nlm.nih.gov/pubmed/27499639
http://dx.doi.org/10.2147/OTT.S105664

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