Lipid Flippase Subunit Cdc50 Mediates Drug Resistance and Virulence in Cryptococcus neoformans

Cryptococcus neoformans is a human fungal pathogen and a major cause of fungal meningitis in immunocompromised individuals. Treatment options for cryptococcosis are limited. Of the two major antifungal drug classes, azoles are active against C. neoformans but exert a fungistatic effect, necessitatin...

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Detalles Bibliográficos
Autores principales: Huang, Wei, Liao, Guojian, Baker, Gregory M., Wang, Yina, Lau, Richard, Paderu, Padmaja, Perlin, David S., Xue, Chaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959666/
https://www.ncbi.nlm.nih.gov/pubmed/27165800
http://dx.doi.org/10.1128/mBio.00478-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959666/
https://www.ncbi.nlm.nih.gov/pubmed/27165800
http://dx.doi.org/10.1128/mBio.00478-16

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