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Direct Characterization of Transcription Elongation by RNA Polymerase I

RNA polymerase I (Pol I) transcribes ribosomal DNA and is responsible for more than 60% of transcription in a growing cell. Despite this fundamental role that directly impacts cell growth and proliferation, the kinetics of transcription by Pol I are poorly understood. This study provides direct char...

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Detalles Bibliográficos
Autores principales: Ucuncuoglu, Suleyman, Engel, Krysta L., Purohit, Prashant K., Dunlap, David D., Schneider, David A., Finzi, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959687/
https://www.ncbi.nlm.nih.gov/pubmed/27455049
http://dx.doi.org/10.1371/journal.pone.0159527