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Direct Characterization of Transcription Elongation by RNA Polymerase I
RNA polymerase I (Pol I) transcribes ribosomal DNA and is responsible for more than 60% of transcription in a growing cell. Despite this fundamental role that directly impacts cell growth and proliferation, the kinetics of transcription by Pol I are poorly understood. This study provides direct char...
Autores principales: | Ucuncuoglu, Suleyman, Engel, Krysta L., Purohit, Prashant K., Dunlap, David D., Schneider, David A., Finzi, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959687/ https://www.ncbi.nlm.nih.gov/pubmed/27455049 http://dx.doi.org/10.1371/journal.pone.0159527 |
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