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Role of Adiponectin in Coronary Heart Disease Risk: A Mendelian Randomization Study

RATIONALE: Hypoadiponectinemia correlates with several coronary heart disease (CHD) risk factors. However, it is unknown whether adiponectin is causally implicated in CHD pathogenesis. OBJECTIVE: We aimed to investigate the causal effect of adiponectin on CHD risk. METHODS AND RESULTS: We undertook...

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Detalles Bibliográficos
Autores principales: Borges, Maria Carolina, Lawlor, Debbie A., de Oliveira, Cesar, White, Jon, Horta, Bernardo Lessa, Barros, Aluísio J.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959825/
https://www.ncbi.nlm.nih.gov/pubmed/27252388
http://dx.doi.org/10.1161/CIRCRESAHA.116.308716