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TWIST1 Integrates Endothelial Responses to Flow in Vascular Dysfunction and Atherosclerosis

RATIONALE: Blood flow–induced shear stress controls endothelial cell (EC) physiology during atherosclerosis via transcriptional mechanisms that are incompletely understood. The mechanosensitive transcription factor TWIST is expressed during embryogenesis, but its role in EC responses to shear stress...

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Detalles Bibliográficos
Autores principales: Mahmoud, Marwa M., Kim, Hyejeong Rosemary, Xing, Rouyu, Hsiao, Sarah, Mammoto, Akiko, Chen, Jing, Serbanovic-Canic, Jovana, Feng, Shuang, Bowden, Neil P., Maguire, Richard, Ariaans, Markus, Francis, Sheila E., Weinberg, Peter D., van der Heiden, Kim, Jones, Elizabeth A., Chico, Timothy J.A., Ridger, Victoria, Evans, Paul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959828/
https://www.ncbi.nlm.nih.gov/pubmed/27245171
http://dx.doi.org/10.1161/CIRCRESAHA.116.308870