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TWIST1 Integrates Endothelial Responses to Flow in Vascular Dysfunction and Atherosclerosis
RATIONALE: Blood flow–induced shear stress controls endothelial cell (EC) physiology during atherosclerosis via transcriptional mechanisms that are incompletely understood. The mechanosensitive transcription factor TWIST is expressed during embryogenesis, but its role in EC responses to shear stress...
Autores principales: | Mahmoud, Marwa M., Kim, Hyejeong Rosemary, Xing, Rouyu, Hsiao, Sarah, Mammoto, Akiko, Chen, Jing, Serbanovic-Canic, Jovana, Feng, Shuang, Bowden, Neil P., Maguire, Richard, Ariaans, Markus, Francis, Sheila E., Weinberg, Peter D., van der Heiden, Kim, Jones, Elizabeth A., Chico, Timothy J.A., Ridger, Victoria, Evans, Paul C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959828/ https://www.ncbi.nlm.nih.gov/pubmed/27245171 http://dx.doi.org/10.1161/CIRCRESAHA.116.308870 |
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