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Nox4 Plays a Role in TGF-β–Dependent Lens Epithelial to Mesenchymal Transition
PURPOSE: Transforming growth factor-β induces an epithelial to mesenchymal transition (EMT) in the lens, presented as an aberrant growth and differentiation of lens epithelial cells. Studies in other models of EMT have shown that TGF-β–driven EMT is dependent on the expression of the reactive oxygen...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959837/ https://www.ncbi.nlm.nih.gov/pubmed/27403995 http://dx.doi.org/10.1167/iovs.16-19114 |