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miR-146a-5p inhibits TNF-α-induced adipogenesis via targeting insulin receptor in primary porcine adipocytes

TNF-α is a multifunctional cytokine participating in immune disorders, inflammation, and tumor development with regulatory effects on energy metabolism. Our work focused on the function of TNF-α in adipogenesis of primary porcine adipocytes. TNF-α could suppress the insulin receptor (IR) at the mRNA...

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Detalles Bibliográficos
Autores principales: Wu, Di, Xi, Qian-Yun, Cheng, Xiao, Dong, Tao, Zhu, Xiao-Tong, Shu, Gang, Wang, Li-Na, Jiang, Qing-Yan, Zhang, Yong-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959853/
https://www.ncbi.nlm.nih.gov/pubmed/27324794
http://dx.doi.org/10.1194/jlr.M062497